Pd-Catalyzed C(sp2)–H aminocarbonylation using the Langlois reagent as a carbonyl source
Literature Information
Xiao-Fang Li, Lin-Feng Shi, Xing-Guo Zhang, Xiao-Hong Zhang
A Pd-catalyzed C(sp2)–H aminocarbonylation of aryl carboxamides assisted by an N,S-bidentate directing group was developed, in which cheap and stable sodium trifluoromethanesulfinate was first utilized as a carbonyl source. The reaction can be applicable to a wide range of carboxamides with good functional group tolerance and afford isoindole-1,3-diones in moderate to good yields.
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