Determination of the illegal adulteration of natural healthcare products with chemical drugs using surface-enhanced Raman scattering
Literature Information
Jiawei Wu, Lixia Zhang, Xiangfeng Bu, Peng Li, Bing Zhao, Yuan Tian
The illegal adulteration of natural healthcare products with chemical drugs can result in serious health risks for consumers. Thus there is an urgent need for a fast and precise detection method. In this research, sodium alginate (SA)-silver nanoparticles (AgNPs) were used as a substrate in surface-enhanced Raman scattering (SERS) for determining vardenafil and rosiglitazone maleate (ROS). Sodium alginate can not only reduce silver ions rapidly to AgNPs as reducing agents but can also protect AgNPs from aggregation by its use as a capping agent. The coffee ring effect has also been applied in this research to facilitate the separation and concentration of analytes. A prominent SERS enhancement can be obtained on the ring because of the electromagnetic mechanism. Both of the properties, including the use of SA and the coffee ring effect, make the method more sensitive in detecting the analytes compared to the classical AgNPs, SERS substrate which were produced using the reduction of silver nitrate with sodium citrate. The method displays a linear response for the determination of vardenafil and ROS in the 4.88–488 μg·mL−1 and 4.74–94.7 μg·mL−1 concentration ranges, and the limit of detection is as low as 1.63 μg·mL−1 and 2.20 μg·mL−1, respectively. The method was successfully applied to the detection of vardenafil and ROS in healthcare products, with recoveries between 91.52% to 107.1% and relative standard deviations of less than 4.31%. This method shows good potential for real applications.
Related Literature
How to interpret current–voltage relationships of blocking grain boundaries in oxygen ionic conductors
Seong K. Kim, Sergey Khodorov, Chien-Ting Chen, Sangtae Kim, Igor Lubomirsky
DOI: 10.1039/C3CP00145H
Controlled electrochemical deposition and transformation of hetero-nanoarchitectured electrodes for energy storage
Jonathon Duay, Eleanor Gillette, Junkai Hu
DOI: 10.1039/C3CP50724F
Photoinduced electron transfer of platinum(ii) bipyridine diacetylides linked by triphenylamine- and naphthaleneimide-derivatives and their application to photoelectric conversion systems
Yuma Matsumoto, Mai Tsubamoto, Ryoji Sugimura, Masatoshi Kozaki, Kenshi Kimoto, Munetaka Iwamura, Koichi Nozaki, Naoki Senju, Chiasa Uragami, Yohei Muramatsu, Akinori Konno
DOI: 10.1039/C3CP50182E
Tandem cathode for proton exchange membrane fuel cells
Samira Siahrostami, Mårten E. Björketun, Peter Strasser, Jeff Greeley, Jan Rossmeisl
DOI: 10.1039/C3CP51479J
Influence of adsorption thermodynamics on guest diffusivities in nanoporous crystalline materials
Rajamani Krishna, Jasper M. van Baten
DOI: 10.1039/C3CP50449B
Speciation of adsorbed CO2 on metal oxides by a new 2-dimensional approach: 2D infrared inversion spectroscopy (2D IRIS)
Sergey Sirotin, Philippe Bazin, Françoise Maugé, Arnaud Travert
DOI: 10.1039/C3CP51146D
Structural changes in supercooled Al2O3–Y2O3 liquids
Mark Wilson, Chris J. Benmore, J. K. R. Weber, Paul F. McMillan
DOI: 10.1039/C3CP51209F
Unraveling the atomic structure of Ge-rich sulfide glasses
Gabriel J. Cuello, Shinji Kohara, Chris J. Benmore, David L. Price, Eugene Bychkov
DOI: 10.1039/C3CP50536G
In situ X-ray pair distribution function analysis of geopolymer gel nanostructure formation kinetics
John L. Provis, Breaunnah Bloomer, Neil J. Henson, Katharine Page
DOI: 10.1039/C3CP44342F
K-edge XANES investigation of octakis(DMSO)lanthanoid(iii) complexes in DMSO solution and solid iodides
Paola D'Angelo, Valentina Migliorati, Riccardo Spezia, Simone De Panfilis, Ingmar Persson, Andrea Zitolo
DOI: 10.1039/C3CP50842K
You might also like
What is the market or research trend for N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0)?
N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0) is increasingly being used ...
What precautions should be taken when handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate (CAS: 1050507-06-6)?
When handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate, appropriate p...
What regulatory guidelines apply to diethyldiselane (CAS: 628-39-7)?
Diethyldiselane (CAS: 628-39-7) is classified under the Globally Harmonized Syst...
What is the market or research trend for oxocopper (CAS: 12053-18-8)?
The market for oxocopper (CAS: 12053-18-8) is primarily driven by its use in cat...
What is the market or research trend for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid?
The market for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-c...
What is 2-(1-Pyrrolidinyl)-4-pyridinamine (CAS: 35981-63-6)?
2-(1-Pyrrolidinyl)-4-pyridinamine is a chemical compound with the CAS number 359...
What are the physical and chemical properties of 2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1)?
2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1) is a crystalline sol...
How is (S)-Alpha-allyl-proline hydrochloride (CAS: 129704-91-2) typically synthesized?
(S)-Alpha-allyl-proline hydrochloride is usually synthesized via a Wittig reacti...
What is 3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5)?
3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5) is an organic compound w...
How is Lys-SMCC-DM1 (CAS: 1281816-04-3) typically synthesized?
Lys-SMCC-DM1 is synthesized via a multi-step process involving the coupling of S...
Source Journal
Analyst

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.














![N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-methionylglycine structure N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-methionylglycine structure](https://static.chemtradehub.com/structs/234/23446-03-9-e1e5.webp)