Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction

Literature Information

Publication Date 2018-05-16
DOI 10.1039/C8AN00711J
Impact Factor 4.616
Authors

Xiaotong Feng, Jon Ashley, Tongchang Zhou, Arnab Halder, Yi Sun


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Abstract

Molecularly imprinted nanoparticles (nanoMIPs) are synthesized via a solid-phase approach using RNase as the template. The feasibility of employing the nanoMIPs as RNase inhibitor is successfully demonstrated in reverse transcriptase polymerase chain reaction (RT-PCR) assays, suggesting the tailor-made nanomaterials are very promising for use in routine biological assays.

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