![1-[6-(1H-Imidazol-1-yl)-3-pyridinyl]methanamine structure](https://static.chemtradehub.com/structs/914/914637-08-4-8825.webp "1-[6-(1H-Imidazol-1-yl)-3-pyridinyl]methanamine structure")
Exploiting the conformational-selection mechanism to control the response kinetics of a “smart” DNA hydrogel
Literature Information
Publication Date
2018-04-24
DOI
10.1039/C8AN00337H
Impact Factor
4.616
Authors
Anna J. Simon, Luke T. Walls-Smith
View Original
Abstract
The sequence-specific hybridization and molecular recognition properties of DNA support the construction of stimulus-responsive hydrogels with precisely controlled crosslink geometry. Here we show that, as predicted by the conformational selection mechanism, the response kinetics of such a hydrogel can be tuned over orders of magnitude by modulating the thermodynamic stability of its crosslinks.
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Recommended Compounds
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Molecular Formula:
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Molecular Formula:
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