Fluorescent and “breathable” CO2 responsive vesicles inspired from green fluorescent protein
Literature Information
Publication Date
2017-09-21
DOI
10.1039/C7PY00963A
Impact Factor
5.582
Authors
Lei Xu, Ning Ren, Ji Pang, Hongping Deng, Xinyuan Zhu, Mo Sun, Deyue Yan
View Original
Abstract
The design of green fluorescent protein (GFP) chromophore labeled, CO2 responsive vesicles that can mimic the breathing of jellyfish is described. The vesicles were obtained via the self-assembly of a di-block copolymer bearing a hydrophilic poly(ethylene glycol) (PEG) segment and a hydrophobic, CO2 responsive poly((diethylamino)ethyl methacrylate) (PDEAEMA) segment, with a GFP chromophore between the two blocks. Like the breathing of a jellyfish, the vesicles’ size and fluorescence changed significantly upon exposure to CO2, as confirmed by morphology observation and fluorescence measurements. Further analysis suggested that the “breathing” of the vesicles is reversible under a continuous CO2/N2 gas flow. The “breathing” behavior of the fluorescent vesicles was also directly observable under a confocal microscope.
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Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
Recommended Compounds
5-(2-Methyl-3-furyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS Number:
346464-59-3
Molecular Formula:
C13H11N3OS
Ethyl 2,4-bis(trifluoromethyl)-5-pyrimidinecarboxylate
CAS Number:
188781-15-9
Molecular Formula:
C9H6F6N2O2
![5,10-Dihydroindeno[2,1-a]indene structure](https://static.chemtradehub.com/structs/654/6543-29-9-71ca.webp "5,10-Dihydroindeno[2,1-a]indene structure")
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