Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodine–magnesium exchange reaction
Literature Information
Greta Varchi, Christiane Kofink, David M. Lindsay, Alfredo Ricci, Paul Knochel
The successive addition of PhMgCl and i-PrMgCl to functionalised iodoanilines allows their conversion to the corresponding amino-functionalised Grignard reagents, which react smoothly with a range of electrophiles in high yield.
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