A novel AlEt3-promoted tandem reductive rearrangement of 1-benzyloxy-2,3-epoxides: new route to 2-quaternary 1,3-diol units

Literature Information

Publication Date 2003-02-25
DOI 10.1039/B209948A
Impact Factor 6.222
Authors

De Run Li, Wu Jiong Xia, Yong Qiang Tu, Fu Min Zhang, Lei Shi


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Abstract

A novel and highly stereoselective tandem rearrangement–reduction reaction of 1-benzyloxy-2,3-epoxide, under the promotion of triethylaluminum (AlEt3), has been developed to construct a quaternary stereocenter and the hydroxymethyl attached to the carbon center in one-step.

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