Gelatin gels as multi-element calibration standards in LA-ICP-MS bioimaging: fabrication of homogeneous standards and microhomogeneity testing

Literature Information

Publication Date 2017-08-18
DOI 10.1039/C7AN01361B
Impact Factor 4.616
Authors

Martin Šala, Vid S. Šelih, Johannes T. van Elteren


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Abstract

Highly homogeneous multi-element gelatin calibration standards were fabricated for quantitative LA-ICP-MS bioimaging. Heterogeneity issues caused by the so-called “coffee-stain” and/or “Marangoni” effects were found to be element-dependent but could be circumvented by careful selection of drying/setting conditions. A micro-homogeneity test was developed for certification of the standards.

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