MeOTf-catalyzed annulation of aldehydes and arylalkynes leading to 2,3-disubstituted indanones

Literature Information

Publication Date 2016-07-12
DOI 10.1039/C6QO00253F
Impact Factor 5.281
Authors

Yu Liu, Peng Zhao, Bo Zhang


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Abstract

The MeOTf-catalyzed construction of indanones via arylalkyne–aldehyde metathesis and subsequent Nazarov cyclization has been reported. This reaction represents a sustainable and atom-economical approach for the preparation of indanones from readily available substrates with high stereoselectivity.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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