Enantioselective gold-catalyzed intermolecular [2 + 2]-cycloadditions of 3-styrylindoles with N-allenyl oxazolidinone

Literature Information

Publication Date 2016-04-20
DOI 10.1039/C6QO00087H
Impact Factor 5.281
Authors

Haoxiang Hu, Yidong Wang, Deyun Qian, Zhan-Ming Zhang, Lu Liu


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Abstract

The enantioselective intermolecular [2 + 2] cycloaddition of 3-styrylindoles with N-allenyl oxazolidinone has been achieved for the first time by the employment of a Xiang-Phos derived chiral gold-catalyst. The corresponding cycloadducts could be obtained in good yields (up to 95%) with up to 95% ee.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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