C–H borylation: a tool for molecular diversification

Literature Information

Publication Date 2023-12-19
DOI 10.1039/D3QO01931D
Impact Factor 5.281
Authors

Saikat Guria, Mirja Md Mahamudul Hassan, Buddhadeb Chattopadhyay


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Abstract

Iridium-catalyzed C–H activation and borylation has become as a powerful synthetic tool in the past few decades because of the widespread applicability and versatility of organoboron compounds. This reaction is currently receiving extensive research interest in both academia and pharmaceutical industries because of its ability to attain a high degree of molecular complexity from simple building blocks. This review aims to highlight the implementation of C–H activation and borylation strategies in tandem one-pot transformations for the synthesis of complex natural products, for the late-stage modifications of bio-active molecules and pharmaceuticals, and for the functionalization of aromatic polycyclic systems used in materials chemistry.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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