Manganese(ii)-catalyzed modular synthesis of isoquinolines from vinyl isocyanides and hydrazines
Literature Information
Publication Date
2016-02-22
DOI
10.1039/C6QO00048G
Impact Factor
5.281
Authors
Hong Mao, Mingchun Gao, Bingxin Liu
View Original
Abstract
An efficient manganese(II)-catalyzed oxidative radical cascade reaction was developed for the modular synthesis of multi-substituted isoquinolines from easily accessible vinyl isocyanides and hydrazines. Pyrrolo[1,2-a]quinoxalines and phenanthridines could also be afforded efficiently by this method and a wide range of alkyl, (hetero)aryl and alkoxycarbonyl substitutions could be easily introduced.
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Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
![[2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-3-yl]dicyclohexylphosphane structure](https://static.chemtradehub.com/structs/787/787618-22-8-dda2.webp "[2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-3-yl]dicyclohexylphosphane structure")
[2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-3-yl]dicyclohexylphosphane
CAS Number:
787618-22-8
Molecular Formula:
C30H43O2P
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