Injectable cationic hydrogels with high antibacterial activity and low toxicity

Literature Information

Publication Date 2016-08-17
DOI 10.1039/C6PY01346E
Impact Factor 5.582
Authors

Hong Du, Xuxia Yao, Xiaodong Li, Zhiquan Shen


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Abstract

Antibacterial materials have always suffered from high toxicity. In this study, we fabricated injectable and biodegradable hydrogels utilizing poly(hexamethylene guanidine) hydrochloride and poly(ethylene glycol) as the backbone through a thiol–ene “click” reaction under physiological conditions, and they showed remarkably low toxicity and high and broad-spectrum antibacterial activity.

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Polymer Chemistry

Polymer Chemistry
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