The removal of disulfide bonds in amylin oligomers leads to the conformational change of the ‘native’ amylin oligomers

Literature Information

Publication Date 2016-04-13
DOI 10.1039/C6CP01196A
Impact Factor 3.676
Authors

Lucia Tudorachi


View Original

Abstract

The α-helical structure of the N-terminus of the ‘native’ amylin Lys1–Cys7 consists of a disulfide bond between Cys2 and Cys7. The ‘native’ amylin oligomers demonstrate polymorphic states. Removal of the disulfide bonds in the ‘native’ amylin oligomers decreases the polymorphism and induces the formation of longer stable cross-β strands in the N-termini.

Related Literature

Radiolysis of crown ether–ionic liquid systems: identification of radiolytic products and their effect on the removal of Sr2+ from nitric acid

Yinyong Ao, Weijin Yuan, Tianlin Yu, Jing Peng, Jiuqiang Li, Maolin Zhai, Long Zhao

2014-12-11 Paper

DOI: 10.1039/C4CP04294H

Topological states modulation of Bi and Sb thin films by atomic adsorption

Hongmei Liu, Xiaoli Wang, Guangliang Cui, Pinhua Zhang, Dapeng Zhao, Shuaihua Ji

2014-12-10 Paper

DOI: 10.1039/C4CP04502E

Moderate band-gap-broadening induced high separation of electron–hole pairs in Br substituted BiOI: a combined experimental and theoretical investigation

Hongwei Huang, Xiaowei Li, Xu Han, Na Tian, Yihe Zhang, Tierui Zhang

2014-12-15 Paper

DOI: 10.1039/C4CP04842C

Pressure-induced phase transition of BiOF: novel two-dimensional layered structures

Dawei Zhou, Chunying Pu, Chaozheng He, Cheng Lu, Gang Bao

2015-01-06 Paper

DOI: 10.1039/C4CP05142D

Galvanic deposition of Rh and Ru on randomly structured Ti felts for the electrochemical NH3 synthesis

Kurt Kugler, Mareike Luhn, Jean André Schramm, Khosrow Rahimi

2014-12-16 Paper

DOI: 10.1039/C4CP05501B

Nanometer-sized dynamic entities in an aqueous system

E. Mamontov, P. Zolnierczuk, M. Ohl

2015-01-05 Paper

DOI: 10.1039/C4CP05081A

Constrained control landscape for population transfer in a two-level system

Katharine Moore Tibbetts, Herschel Rabitz

2014-12-11 Paper

DOI: 10.1039/C4CP04792C

Accurate calibration and control of relative humidity close to 100% by X-raying a DOPC multilayer

Yicong Ma, Sajal K. Ghosh, Sambhunath Bera, Zhang Jiang, Stephanie Tristram-Nagle, Laurence B. Lurio, Sunil K. Sinha

2014-12-15 Paper

DOI: 10.1039/C4CP04407J

You might also like

Compound Q&A

What precautions should be taken when handling 4-(2-Furylmethyl)thiomorpholine 1,1-dioxide (CAS: 79206-94-3)?

When handling 4-(2-Furylmethyl)thiomorpholine 1,1-dioxide (CAS: 79206-94-3), it ...

79206-94-34-(2-Furylmethyl)thi...
Compound Q&A

What precautions should be taken when handling 4-Chloro-N-[2-(4-morpholinyl)ethyl]benzamide (CAS: 71320-77-9)?

When handling 4-Chloro-N-[2-(4-morpholinyl)ethyl]benzamide (CAS: 71320-77-9), it...

71320-77-94-Chloro-N-[2-(4-mor...
Compound Q&A

How should waste containing 2-[2-(2-Methoxyethoxy)ethoxy]ethyl 4-methylbenzenesulfonate (CAS: 62921-74-8) be handled?

Waste containing this compound (CAS: 62921-74-8) should be handled according to ...

62921-74-82-[2-(2-Methoxyethox...
Compound Q&A

How should waste containing (S)-Methyl 2-amino-3-cyclohexylpropanoate be handled?

Waste containing (S)-Methyl 2-amino-3-cyclohexylpropanoate should be collected i...

40056-18-6(S)-Methyl 2-amino-3...
166882-70-85-({4-[(2S,4R)-4-Hyd...
Compound Q&A

Are there alternatives to (2E)-3-(3,4-Dichlorophenyl)acrylic acid (CAS: 7312-27-8) in synthesis?

There are several alternatives to (2E)-3-(3,4-Dichlorophenyl)acrylic acid in syn...

7312-27-8(2E)-3-(3,4-Dichloro...
Compound Q&A

How should Ethyl 6-(2-nitrophenyl)imidazo[2,1-b][1,3]thiazole-3-carboxylate (CAS: 925437-84-9) be stored?

Ethyl 6-(2-nitrophenyl)imidazo[2,1-b][1,3]thiazole-3-carboxylate (CAS: 925437-84...

925437-84-9Ethyl 6-(2-nitrophen...
Compound Q&A

How should waste containing 2-(1,3-Thiazol-2-yl)ethanamine (CAS: 18453-07-1) be handled?

Waste containing 2-(1,3-Thiazol-2-yl)ethanamine (CAS: 18453-07-1) should be coll...

18453-07-12-(1,3-Thiazol-2-yl)...
Compound Q&A

How is Methyl 5-iodo-2-methylbenzoate (CAS: 103440-54-6) typically synthesized?

Methyl 5-iodo-2-methylbenzoate can be synthesized through the iodination of meth...

103440-54-6Methyl 5-iodo-2-meth...
Compound Q&A

How is 5-Chloro[1,2,4]triazolo[1,5-a]pyridine (CAS: 1427399-34-5) typically synthesized?

5-Chloro[1,2,4]triazolo[1,5-a]pyridine is commonly synthesized via the condensat...

1427399-34-55-Chloro[1,2,4]triaz...

Source Journal

Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics
CiteScore: 5.5
Self-citation Rate: 10.3%
Articles per Year: 3036

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.