Raman spectroscopy in microsurgery: impact of operating microscope illumination sources on data quality and tissue classification

Literature Information

Publication Date 2016-10-31
DOI 10.1039/C6AN02061E
Impact Factor 4.616
Authors

Joannie Desroches, Audrey Laurence, Michael Pinto, Marie-Andrée Tremblay, Kevin Petrecca, Frédéric Leblond


View Original

Abstract

Ambient light artifacts can confound Raman spectroscopy measurements performed in a clinical setting such as during open surgery. However, requiring light sources to be turned off during intraoperative spectral acquisition can be impractical because it can slow down the procedure by requiring surgeons to acquire data under light conditions different from the routine clinical practice. Here a filter system is introduced allowing in vivo Raman spectroscopy measurements to be performed with the light source of a neurosurgical microscope turned on, without interfering with the standard procedure. Ex vivo and in vivo results on calf and human brain, respectively, show that when the new filter system is used there is no significant difference between Raman spectra acquired under pitch dark conditions or with the microscope light source turned on. This is important for the clinical translation of Raman spectroscopy because of the resulting decrease in total imaging time for each measurement and because the surgeon can now acquire spectroscopic data with no disruption of the surgical workflow.

Related Literature

A variable temperature synchrotron X-ray diffraction study of the ferroelastic double perovskite Ba2GdMoO6

Thomas K. Wallace, Ross H. Colman, Abbie C. Mclaughlin

2013-01-03 Paper

DOI: 10.1039/C2CP43732E

An all-cotton-derived, arbitrarily foldable, high-rate, electrochemical supercapacitor

Jiangli Xue, Yang Zhao, Huhu Cheng, Chuangang Hu, Yue Hu, Yuning Meng, Huibo Shao, Zhipan Zhang, Liangti Qu

2013-04-15 Communication

DOI: 10.1039/C3CP51571K

Self-discharge of electrochemical double layer capacitors

Andrzej Lewandowski, Pawel Jakobczyk, Maciej Galinski, Marcin Biegun

2013-03-22 Perspective

DOI: 10.1039/C3CP44612C

Powder crystallography of pharmaceutical materials by combined crystal structure prediction and solid-state 1H NMR spectroscopy

Maria Baias, Cory M. Widdifield, Jean-Nicolas Dumez, Hugh P. G. Thompson, Timothy G. Cooper, Elodie Salager, Sirena Bassil, Robin S. Stein, Anne Lesage, Graeme M. Day, Lyndon Emsley

2013-02-19 Paper

DOI: 10.1039/C3CP41095A

Local electronic structure of aqueous zinc acetate: oxygen K-edge X-ray absorption and emission spectroscopy on micro-jets

Edlira Suljoti, Kai F. Hodeck, Kathrin M. Lange, Mikhail A. Soldatov

2013-04-17 Communication

DOI: 10.1039/C3CP50686J

A time resolved high energy X-ray diffraction study of cooling liquid SiO2

C. J. Benmore, M. C. Wilding, S. K. Tumber

2013-04-05 Paper

DOI: 10.1039/C3CP44347G

ZnO nanoparticle based highly efficient CdS/CdSe quantum dot-sensitized solar cells

Chunhui Li, Lei Yang, Junyan Xiao, Yih-Chyng Wu, Martin Søndergaard, Yanhong Luo, Dongmei Li, Qingbo Meng, Bo Brummerstedt Iversen

2013-03-27 Communication

DOI: 10.1039/C3CP50365H

Sieving di-branched from mono-branched and linear alkanes using ZIF-8: experimental proof and theoretical explanation

Marjo C. Mittelmeijer-Hazeleger, Miguel Angelo Granato, Vanessa F. Duarte Martins, Alírio E. Rodrigues, Gadi Rothenberg

2013-05-02 Paper

DOI: 10.1039/C3CP44381G

How to interpret current–voltage relationships of blocking grain boundaries in oxygen ionic conductors

Seong K. Kim, Sergey Khodorov, Chien-Ting Chen, Sangtae Kim, Igor Lubomirsky

2013-04-18 Communication

DOI: 10.1039/C3CP00145H

An ab initio investigation of Li2M0.5N0.5SiO4 (M, N = Mn, Fe, Co Ni) as Li-ion battery cathode materials

Sirous Asgari, Doretta Capsoni, Piercarlo Mustarelli

2013-04-23 Communication

DOI: 10.1039/C3CP51481A

You might also like

Compound Q&A

What is the market or research trend for N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0)?

N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0) is increasingly being used ...

52818-63-0N-(4-Methoxybenzyl)-...
Compound Q&A

What precautions should be taken when handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate (CAS: 1050507-06-6)?

When handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate, appropriate p...

1050507-06-6Ethyl 4-(2-chlorophe...
Compound Q&A

What regulatory guidelines apply to diethyldiselane (CAS: 628-39-7)?

Diethyldiselane (CAS: 628-39-7) is classified under the Globally Harmonized Syst...

628-39-7Diethyldiselane
Compound Q&A

What is the market or research trend for oxocopper (CAS: 12053-18-8)?

The market for oxocopper (CAS: 12053-18-8) is primarily driven by its use in cat...

12053-18-8oxocopper; oxo-(oxoc...
Compound Q&A

What is the market or research trend for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid?

The market for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-c...

1268519-54-55-{[(2-Methyl-2-prop...
Compound Q&A

What is 2-(1-Pyrrolidinyl)-4-pyridinamine (CAS: 35981-63-6)?

2-(1-Pyrrolidinyl)-4-pyridinamine is a chemical compound with the CAS number 359...

35981-63-62-(1-Pyrrolidinyl)-4...
Compound Q&A

What are the physical and chemical properties of 2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1)?

2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1) is a crystalline sol...

91556-75-12-(3-Pyridinyl)-1-az...
Compound Q&A

How is (S)-Alpha-allyl-proline hydrochloride (CAS: 129704-91-2) typically synthesized?

(S)-Alpha-allyl-proline hydrochloride is usually synthesized via a Wittig reacti...

129704-91-2(S)-Alpha-allyl-prol...
Compound Q&A

What is 3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5)?

3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5) is an organic compound w...

4857-42-53-Methyl-1,2-oxazole...
Compound Q&A

How is Lys-SMCC-DM1 (CAS: 1281816-04-3) typically synthesized?

Lys-SMCC-DM1 is synthesized via a multi-step process involving the coupling of S...

1281816-04-3Lys-SMCC-DM1

Source Journal

Analyst

Analyst
CiteScore: 7.8
Self-citation Rate: 5.6%
Articles per Year: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.