Glycosylation via remote activation of anomeric leaving groups: development of 2-(2-propylsulfinyl)benzyl glycosides as novel glycosyl donors

Literature Information

Publication Date 2015-12-14
DOI 10.1039/C5QO00359H
Impact Factor 5.281
Authors

Penghua Shu, Wang Yao, Xiong Xiao, Jiuchang Sun, Xiang Zhao, Yueqi Zhao, Yang Xu, Jinyi Tao, Guangmin Yao, Jing Zeng


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Abstract

2-(2-Propylsulfinyl)benzyl glycoside was designed as a new type of glycosyl donor which could be activated via remote mode. This glycosyl donor and its reduced form could act as active and latent donors respectively in a latent-active glycosylation strategy. Details of the discovery of this novel glycosyl donor are reported in this article.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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