Direct borylation of benzyl alcohol and its analogues in the absence of bases

Literature Information

Publication Date 2015-09-10
DOI 10.1039/C5QO00243E
Impact Factor 5.281
Authors

Zhi-Chao Cao, Fei-Xian Luo, Wen-Juan Shi


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Abstract

Direct borylation of arylmethanols to synthesize important and useful benzylboronates was carried out through Pd(OAc)2-catalyzed sp3 C–O activation. This borylation is compatible with various functional groups under mild conditions in the absence of any bases, offering an atom- and step-economical way to produce benzylboron compounds.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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