An injectable drug-loaded hydrogel using a “clickable” amphiphilic triblock copolymer as a precursor
Literature Information
Publication Date
2015-09-24
DOI
10.1039/C5PY01383F
Impact Factor
5.582
Authors
Lilong Gao, Guangyu Zha, Qiaojie Luo, Weipu Zhu, Zhiquan Shen, Xiaodong Li
View Original
Abstract
We developed a facile strategy to prepare an injectable drug-loaded hydrogel with chemical crosslinkages. A PCL-POEGM-PCL amphiphilic triblock copolymer was synthesized in “one pot” by a combination of polycondensation and ring-opening polymerization, which can disperse hydrophobic drugs in aqueous solution and be crosslinked by POEGMS under physiological conditions.
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Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
Recommended Compounds
Benzyl 3-(aminomethyl)piperidine-1-carboxylate hydrochloride
CAS Number:
1186663-23-9
Molecular Formula:
C14H21ClN2O2
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