Gold nanoparticle/polymer nanocomposite for highly sensitive drug–DNA interaction

Literature Information

Publication Date 2015-02-24
DOI 10.1039/C5AN00061K
Impact Factor 4.616
Authors

F. Kuralay, A. Erdem


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Abstract

The interaction of the anticancer drug mitomycin C (MC) and DNA immobilized on gold a nanoparticle/polyvinylferrocenium (AuNP/PVF+) coated electrode is presented. This is the first attempt to prepare a biocompatible nanoparticle/redox polymer composite in a one-step and easy electropolymerization procedure and then use the coated electrode for MC–DNA interaction. The prepared electrode exhibits high sensitivity for the investigation of drug–DNA interaction.

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