Introducing deep eutectic solvents as biorenewable media for Au(i)-catalysed cycloisomerisation of γ-alkynoic acids: an unprecedented catalytic system
Literature Information
María J. Rodríguez-Álvarez, Cristian Vidal, Josefina Díez, Joaquín García-Álvarez
Cycloisomerisation of γ-alkynoic acids into cyclic enol-lactones was conveniently performed, for the first time, in the eutectic mixture 1ChCl/2Urea under standard bench experimental conditions (at room temperature, under air and in the absence of co-catalysts) by using a new iminophosphorane–Au(I) complex as the catalyst. Furthermore, the catalytic system could be recycled up to four runs.
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![Sodium (2Z)-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)-2-heptenoate structure Sodium (2Z)-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)-2-heptenoate structure](https://static.chemtradehub.com/structs/811/81129-83-1-441c.webp)