2-(3'-Chlorobiphenyl-3-yl)-4,6-diphenyl-1,3,5-triazine
CAS Number:
1443049-83-9
Molecular Formula:
C27H18ClN3
Novel integrated and portable endotoxin detection system based on an electrochemical biosensor
Literature Information
Publication Date
2014-11-13
DOI
10.1039/C4AN01324G
Impact Factor
4.616
Authors
Fernando Arizti, Susana Sánchez-Gómez, Guillermo Martínez de Tejada, Klaus Brandenburg
View Original
Abstract
This paper describes the design, implementation and validation of a sensitive and integral technology solution for endotoxin detection. The unified and portable platform is based on the electrochemical detection of endotoxins using a synthetic peptide immobilized on a thin-film biosensor. The work covers the fabrication of an optimized sensor, the biofunctionalization protocol and the design and implementation of the measuring and signalling elements (a microfluidic chamber and a portable potentiostat–galvanostat), framed ad hoc for this specific application. The use of thin-film technologies to fabricate the biosensing device and the application of simple immobilization and detection methods enable a rapid, easy and sensitive technique for in situ and real time LPS detection.
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Analyst
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