![5-Bromoimidazo[1,2-a]pyridine structure](https://static.chemtradehub.com/structs/692/69214-09-1-d8e2.webp "5-Bromoimidazo[1,2-a]pyridine structure")
Green electrochemical sensing platforms: utilizing hydroxyapatite derived from natural fish scales as a novel electrochemical material for the sensitive detection of kidney injury molecule 1 (KIM-1)
Literature Information
Publication Date
2014-09-05
DOI
10.1039/C4AN00957F
Impact Factor
4.616
Authors
Ying Zhang, Wei Zhang, Qing Zhang, Kaiyang Li, Wei Liu, Yong Liu, Craig E. Banks
View Original
Abstract
Urinary KIM-1 is an ideal biomarker for acute kidney injury diagnosis. The proof-of-concept is demonstrated by utilizing the hydroxyapatite derived from natural fish scales as an electrode material, where the sensing of KIM-1 is shown to be possible for the first time with a linear range from 0.01 to 0.20 μg mL−1 and a detection limit of 0.017 μg mL−1 under model conditions; proof-of-concept is demonstrated in spiked urine.
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