![Sodium 6-amino-3-[(E)-{4-[(E)-(4-aminophenyl)diazenyl]-2-methoxy-5-methylphenyl}diazenyl]-4-hydroxy-2-naphthalenesulfonate structure](https://static.chemtradehub.com/structs/294/2945-96-2-092f.webp "Sodium 6-amino-3-[(E)-{4-[(E)-(4-aminophenyl)diazenyl]-2-methoxy-5-methylphenyl}diazenyl]-4-hydroxy-2-naphthalenesulfonate structure")
Sodium 6-amino-3-[(E)-{4-[(E)-(4-aminophenyl)diazenyl]-2-methoxy-5-methylphenyl}diazenyl]-4-hydroxy-2-naphthalenesulfonate
CAS Number:
2945-96-2
Molecular Formula:
C24H21N6NaO5S
Functionalized viral nanoparticles as ultrasensitive reporters in lateral-flow assays
Literature Information
Publication Date
2013-07-25
DOI
10.1039/C3AN00891F
Impact Factor
4.616
Authors
Meena Adhikari, Sagar Dhamane, Anna E. V. Hagström, Gavin Garvey, Wen-Hsiang Chen, Katerina Kourentzi, Ulrich Strych
View Original
Abstract
Two types of viral nanoparticles were functionalized with target-specific antibodies and multiple copies of an enzymatic reporter (horseradish peroxidase). The particles were successfully integrated into an immunochromatographic assay detecting MS2 bacteriophage, a model for viral pathogens. The sensitivity of the assay was greatly superior to conventional gold nanoparticle lateral flow assays, and results could easily be evaluated, even without advanced lab instruments.
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Source Journal
Analyst
CiteScore:
7.8
Self-citation Rate:
5.6%
Articles per Year:
653
Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
Recommended Compounds
(R)-2-amino-3-(benzyloxy)propan-1-ol hydrochloride
CAS Number:
58577-95-0
Molecular Formula:
C10H16ClNO2
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