N,N-dimethyl(piperidin-4-yl)methanamine hydrochloride
CAS Number:
172281-72-0
Molecular Formula:
C8H20Cl2N2
Functionalized viral nanoparticles as ultrasensitive reporters in lateral-flow assays
Literature Information
Publication Date
2013-07-25
DOI
10.1039/C3AN00891F
Impact Factor
4.616
Authors
Meena Adhikari, Sagar Dhamane, Anna E. V. Hagström, Gavin Garvey, Wen-Hsiang Chen, Katerina Kourentzi, Ulrich Strych
View Original
Abstract
Two types of viral nanoparticles were functionalized with target-specific antibodies and multiple copies of an enzymatic reporter (horseradish peroxidase). The particles were successfully integrated into an immunochromatographic assay detecting MS2 bacteriophage, a model for viral pathogens. The sensitivity of the assay was greatly superior to conventional gold nanoparticle lateral flow assays, and results could easily be evaluated, even without advanced lab instruments.
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Source Journal
Analyst
CiteScore:
7.8
Self-citation Rate:
5.6%
Articles per Year:
653
Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
Recommended Compounds
![2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole structure](https://static.chemtradehub.com/structs/122/1226781-80-1-09d5.webp "2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole structure")
2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole
CAS Number:
1226781-80-1
Molecular Formula:
C6H9N3O2S
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