Synthesis and bioconjugation of first alkynylated poly(dithieno[3,2-b:2′,3′-d]pyrrole)s
Literature Information
Publication Date
2017-11-06
DOI
10.1039/C7PY01528C
Impact Factor
5.582
Authors
Sylvia Schmid, Jasmina Gačanin, Peter Bäuerle
View Original
Abstract
First synthesis of an alkynylated dithieno[3,2-b:2′,3′-d]pyrrole (DTP) monomer was developed, which allows electrochemical polymerization on platinum and indium tin oxide (ITO) electrodes. The obtained DTP-based polymer (pDTP) was successfully post-modified with redox active and biological entities via bio-orthogonal 1,3-dipolar cycloaddition reactions and [2 + 2]-cycloaddition. In vitro experiments with A549-human lung carcinoma cells evidenced the general biocompatibility of the compositionally tuneable pDTP-coated electrodes.
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Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
Recommended Compounds
![4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione structure](https://static.chemtradehub.com/structs/110/1104546-89-5-a600.webp "4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione structure")
4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione
CAS Number:
1104546-89-5
Molecular Formula:
C15H12N2O2
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