A test method to evaluate chronic particulate generation from durable polymer stent coatings: a case study of CYPHER® sirolimus-eluting coronary stents
Literature Information
Judith H. Cohen, Karin M. Balss, Eugena Akerman-Revis, Mark Inderbitzen, James Lisk, Asha Marathe, Robert O'Brien, Elaine Pottinger-Cooper, William Rudd, Cheryl Wendel, George Papandreou, Cynthia A. Maryanoff
In order to predict the long term coating durability of drug-eluting stent (DES) products, we developed a new testing methodology using a novel mechanical tester to evaluate the potential of drug–polymer coatings to generate particles over time. The tester simulates the device radial fatigue expected during in vivo conditions due to expansion and contraction of the implanted vessel. Analysis by Scanning Electron Microscopy (SEM) of particulate collected via an in-line filtration system allows for evaluation of the chronic durability of DES polymer coatings. Data provided within show the durable polymer coating of CYPHER® Stents generates small amounts of particulates upon fatigue indicating coating integrity is maintained even when the DES system is subjected to expansion, deployment, and repetitive cycling modalities.
Related Literature
Energy storage properties of a two-dimensional TiB4 monolayer
Erdong Wu, Shi Liu
DOI: 10.1039/C9CP01864F
Inelastic scattering dynamics of ortho and para hydronium ions, o-H3O+ and p-H3O+, with He at low temperature
Houda El Hanini, Faouzi Najar, Manel Naouai, Nejm-Eddine Jaidane
DOI: 10.1039/C9CP01889A
Giant enhancement of electronic polarizability and the first hyperpolarizability of fluoride-decorated graphene versus graphyne and graphdiyne: insights from ab initio calculations
Xiaojun Li, Jun Lu
DOI: 10.1039/C9CP01118H
Nanoscale PDA disassembly in ionic liquids: structure–property relationships underpinning redox tuning
Marianna Ambrico, Paola Manini, Paolo F. Ambrico, Teresa Ligonzo, Giuseppe Casamassima, Paola Franchi, Luca Valgimigli, Andrea Mezzetta, Cinzia Chiappe, Marco d'Ischia
DOI: 10.1039/C9CP01545K
Size-dependent ion emission asymmetry of free NaCl nanoparticles excited by intense femtosecond laser pulses
E. Antonsson, F. Gerke, L. Merkel, I. Halfpap, B. Langer, E. Rühl
DOI: 10.1039/C9CP00696F
In situ, operando studies on the size and structure of supported Pt catalysts under supercritical conditions by simultaneous synchrotron-based X-ray techniques
Sungwon Lee, Sungsik Lee, Duygu Gerceker, Mrunmayi D. Kumbhalkar, Kamila M. Wiaderek, Madelyn R. Ball, Manos Mavrikakis, James A. Dumesic, Randall E. Winans
DOI: 10.1039/C9CP00347A
Pretransitional behavior of viscoelastic parameters at the nematic to twist-bend nematic phase transition in flexible n-mers
Zeinab Parsouzi, Mojtaba Rajabi, Rony Saha, Prabesh Gyawali, Alan R. Baldwin, Chris Welch, Georg H. Mehl, J. T. Gleeson, Samuel Sprunt
DOI: 10.1039/C9CP00984A
Explaining the optical spectrum of CrF2 and CuF2 model materials: role of the tetragonal to monoclinic instability
J. A. Aramburu, M. Moreno
DOI: 10.1039/C9CP01822K
A heuristic approach for nanodrops on a smooth solid surface
Gersh O. Berim, Eli Ruckenstein
DOI: 10.1039/C9CP01791G
On the preparation and NMR spectroscopic characterization of potassium aluminium tetrahydride KAlH4
Bodo Zibrowius, Michael Felderhoff
DOI: 10.1039/C9CP01059A
You might also like
What are the main uses of 1H-Indazole-6-carbonitrile (CAS: 141290-59-7)?
1H-Indazole-6-carbonitrile finds applications in pharmaceuticals, where it serve...
How should waste containing Dioctyl (2E)-2-butenedioate (CAS: 2997-85-5) be handled?
Waste containing Dioctyl (2E)-2-butenedioate (CAS: 2997-85-5) should be collecte...
What industries use Sodium [(1,2-benzoxazol-3-ylmethyl)sulfonyl]azanide (CAS: 68291-98-5)?
Sodium [(1,2-benzoxazol-3-ylmethyl)sulfonyl]azanide is primarily used in pharmac...
Are there alternatives to Dimethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-pyridinedicarboxylate (CAS: 741709-66-0) in synthesis?
Dimethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-pyridinedicarboxyla...
How should waste containing 2-Fluoro-6-hydrazinopyridine (CAS: 80714-39-2) be handled?
Waste containing 2-Fluoro-6-hydrazinopyridine (CAS: 80714-39-2) should be manage...
What is 6-Formyl-2-pyridinecarboxylic acid (CAS: 499214-11-8)?
6-Formyl-2-pyridinecarboxylic acid is an organic compound with the molecular for...
What is the market or research trend for 3-(3,4-dimethoxyphenyl)-2,5-dimethyl-N-(2-morpholin-4-ylethyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS: 900874-91-1)?
Research trends for this compound indicate a focus on its potential applications...
How is 9H-Tribenzo[b,d,f]azepine (CAS: 29875-73-8) typically synthesized?
9H-Tribenzo[b,d,f]azepine is typically synthesized via a multi-step process invo...
How is 1-Cyclopropyl-7-ethoxy-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 1797982-51-4) typically synthesized?
1-Cyclopropyl-7-ethoxy-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxyli...
How should waste containing Methyl 3-oxo-1,2,3,4-tetrahydro-6-quinoxalinecarboxylate (CAS: 671820-52-3) be handled?
Waste containing Methyl 3-oxo-1,2,3,4-tetrahydro-6-quinoxalinecarboxylate (CAS: ...
Source Journal
Analytical Methods

Analytical Methods welcomes early applications of new analytical and bioanalytical methods and technology demonstrating the potential for societal impact. We require that methods and technology reported in the journal are sufficiently innovative, robust, accurate, and compared to other available methods for the intended application. Developments with interdisciplinary approaches are particularly welcome. Systems should be proven with suitably complex and analytically challenging samples. We encourage developments within, but not limited to, the following technologies and applications: global health, point-of-care and molecular diagnostics biosensors and bioengineering drug development and pharmaceutical analysis applied microfluidics and nanotechnology omics studies, such as proteomics, metabolomics or glycomics environmental, agricultural and food science neuroscience biochemical and clinical analysis forensic analysis industrial process and method development










![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]serine structure N-[(9H-Fluoren-9-ylmethoxy)carbonyl]serine structure](https://static.chemtradehub.com/structs/737/73724-45-5-b0dc.webp)



