Reverse orthogonal strategy for oligosaccharide synthesis‡§

Literature Information

Publication Date 2011-09-05
DOI 10.1039/C1CC13409D
Impact Factor 6.222
Authors

Kohki Fujikawa, N. Vijaya Ganesh, Yih Horng Tan, Keith J. Stine, Alexei V. Demchenko


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Abstract

Herein, we report the invention of a novel expeditious concept for oligosaccharide synthesis. Unlike the classic orthogonal strategy based on leaving groups, the reverse approach is based on orthogonal protecting groups, herein p-methoxybenzyl and 4-pentenoyl, which allows for efficient oligosaccharide assembly in the reverse direction.

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