Mechanochemistry of magnesium oxide revisited: facile derivatisation of pharmaceuticals using coordination and supramolecular chemistry
Literature Information
Publication Date
2010-08-10
DOI
10.1039/C0CC01337D
Impact Factor
6.222
Authors
Ernest H. H. Chow, Fiona C. Strobridge, Tomislav Friščić
View Original
Abstract
Liquid-assisted grinding allows the rapid, waste-free and one-pot synthesis of a variety of magnesium drug derivatives directly from the excipient MgO; such reactivity is relevant for the behaviour of ibuprofen formulations involving MgO and can be used for oxide-based mechanosynthesis of metal–organic salts, discrete complexes and carboxylate clusters involving magnesium and pharmaceutically active ingredients.
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Source Journal
Chemical Communications
CiteScore:
8.6
Self-citation Rate:
4.7%
Articles per Year:
2458
ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry
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