Sensitive and efficient detection of thrombus with fibrin-specific manganese nanocolloids

Literature Information

Publication Date 2009-04-22
DOI 10.1039/B902875G
Impact Factor 6.222
Authors

Dipanjan Pan, Angana Senpan, Todd A. Williams, Mike J. Scott, Patrick J. Gaffney, Samuel A. Wickline, Gregory M. Lanza


View Original

Abstract

In this work, we report novel fibrin targeted “soft-type” manganese-based contrast agents for MRI with the potential to noninvasively image intravascular thrombus which could warrant aggressive medical intervention to preclude subsequent myocardial infarction or stroke.

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ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

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