Polymer/silica hybrid hollow nanospheres with pH-sensitive drug release in physiological and intracellular environments

Literature Information

Publication Date 2009-03-27
DOI 10.1039/B900751B
Impact Factor 6.222
Authors

Yin Ding, Changjing Chen, Rutian Li, Yong Hu, Xiqun Jiang


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Abstract

Hybrid hollow nanospheres of chitosan–silica templated by chitosan–poly(acrylic acid) nanoparticles are fabricated in a complete aqueous system, which provide a pH-sensitive switch in physiological and sub-cell environments for the release of loaded drug.

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Chemical Communications

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