3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters

Literature Information

Publication Date 2008-11-05
DOI 10.1039/B815888F
Impact Factor 6.222
Authors

Jaskiranjit Kang, Jonathan P. Richardson, Derek Macmillan


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Abstract

Peptides and proteins fragment sequence-specifically in the presence of 3-mercaptopropionic acid to afford thioesters which can be used in native chemical ligation reactions.

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