Covalent double level dynamic combinatorial libraries: selectively addressable exchange processes

Literature Information

Publication Date 2008-09-30
DOI 10.1039/B808565J
Impact Factor 6.222
Authors

A. Gastón Orrillo, Andrea M. Escalante, Ricardo L. E. Furlan


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Abstract

Hydrazones and disulfides have been combined in one dynamic system: hydrazones were exchanged by acid catalysis in the presence of disulfide and a thiol group without interference; neutralization of the reaction medium turns off the exchange of hydrazones and, at the same time, activates thiolate–disulfide exchange.

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