SERRS immunoassay for quantitative human CRP analysis‡§

Literature Information

Publication Date 2008-06-25
DOI 10.1039/B808087A
Impact Factor 4.616
Authors

Fiona M. Campbell, Andrew Ingram, Paul Monaghan, Jon Cooper, Naveed Sattar, P. David Eckersall, Duncan Graham


View Original

Abstract

SERRS has been used for the first time for the measurement of C-reactive protein (CRP) in an immunoassay. CRP, a biological marker for the diagnosis of infection and inflammation, is quantified in an ELISA using conventional reagents, but the usual colorimetric detection step is replaced by SERRS detection, offering improved sensitivity and potential for multiplexing analysis.

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