Biomimetic trifunctional organocatalyst showing a great acceleration for the transesterification between vinyl ester and alcohol

Literature Information

Publication Date 2008-01-22
DOI 10.1039/B718763G
Impact Factor 6.222
Authors

Tadashi Ema, Daisuke Tanida, Tatsuya Matsukawa, Takashi Sakai


View Original

Abstract

Trifunctional organocatalysts 1a and 1b mimicking the active site of serine hydrolases showed high catalytic activity with up to a 3 700 000-fold acceleration for the acyl-transfer reactions from vinyl trifluoroacetate to alcohol.

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Contents and Highlights in Chemical Biology

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DOI: 10.1039/B918025G

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