Nickeladihydrofuran. Key intermediate for nickel-catalyzed reaction of alkyne and aldehyde

Literature Information

Publication Date 2008-01-21
DOI 10.1039/B717261C
Impact Factor 6.222
Authors

Sensuke Ogoshi, Tomoya Arai, Masato Ohashi, Hideo Kurosawa


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Abstract

The formation of a nickeladihydrofuran by oxidative cyclization of an alkyne and an aldehyde with nickel(0) has been demonstrated; the transformation of the nickeladihydrofuran into an enone by decomposition, a lactone by carbonylation and an allylic alcohol by treatment with ZnMe2 suggests that nickeladihydrofuran is an important key intermediate in a variety of catalytic reactions.

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