Nickeladihydrofuran. Key intermediate for nickel-catalyzed reaction of alkyne and aldehyde
Literature Information
Sensuke Ogoshi, Tomoya Arai, Masato Ohashi, Hideo Kurosawa
The formation of a nickeladihydrofuran by oxidative cyclization of an alkyne and an aldehyde with nickel(0) has been demonstrated; the transformation of the nickeladihydrofuran into an enone by decomposition, a lactone by carbonylation and an allylic alcohol by treatment with ZnMe2 suggests that nickeladihydrofuran is an important key intermediate in a variety of catalytic reactions.
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![4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl acetate structure 4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl acetate structure](https://static.chemtradehub.com/structs/740/740081-22-5-f58f.webp)
