Spirocyclic helical compounds as binding agents for bulged RNA, including HIV-2 TAR
Literature Information
Ziwei Xiao, Na Zhang, Yiqing Lin, Graham B. Jones, Irving H. Goldberg
Based on fluorescence binding studies and 1D 1H NMR studies, designed synthetic analogues of NCSi-gb bind specifically with two-base bulged RNA, including HIV-2 TAR RNA, making them potential lead compounds for antiviral drug development.
Recommended Journals

Nature

Pharmacological Reviews

Journal of Catalysis

Journal of Medicinal Chemistry

Journal of Organometallic Chemistry

Journal of Heterocyclic Chemistry

Science

Proceedings of the National Academy of Sciences of the United States of America

European Journal of Wood and Wood Products

Organic Preparations and Procedures International
Related Literature
Helical supramolecular host with aquapores anchoring alternate molecules of helical water chains‡
Arindam Mukherjee, Manas K. Saha, Munirathinam Nethaji, Akhil R. Chakravarty
DOI: 10.1039/B316275C
Living cationic polymerisation of styrene in an ionic liquid
R. Vijayaraghavan, D. R. MacFarlane
DOI: 10.1039/B315100J
Hydrogen adsorption in the nanoporous metal-benzenedicarboxylate M(OH)(O2C–C6H4–CO2) (M = Al3+, Cr3+), MIL-53
Gérard Férey, Michel Latroche, Christian Serre, Franck Millange, Thierry Loiseau, Annick Percheron-Guégan
DOI: 10.1039/B308903G
Electrospray mass spectrometry of undiluted ionic liquids
Glen P. Jackson, Douglas C. Duckworth
DOI: 10.1039/B314754A
Self-indicating amine scavenger resins
Jin Ku Cho, Peter D. White, Wolfgang Klute, Tony W. Dean, Mark Bradley
DOI: 10.1039/B315426B
Unexpected cleavage of tetrahydrofuran by catalytic reductive lithiation
Stéphane Streiff, Nigel Ribeiro, Laurent Désaubry
DOI: 10.1039/B312972A
Encapsulation of paramagnetic 3d1-vanadium(iv) in an antiferromagnetically coupled dodecanuclear copper(ii) cage
Arindam Mukherjee, Munirathinam Nethaji, Akhil R. Chakravarty
DOI: 10.1039/B310521K
Significant and differential acceleration of dephosphorylation of the insecticides, paraoxon and parathion, caused by alkali metal ethoxides
Ik-Hwan Um, Sang-Eun Jeon, Mi-Hwa Baek, Hye-Ran Park
DOI: 10.1039/B310055C
Synthesis and characterization of novel chiral sulfonato–salen–manganese(iii) complex in a zinc–aluminium LDH host
Samiran Bhattacharjee, James A. Anderson
DOI: 10.1039/B315325H
VIII(OH){O2C–C6H4–CO2}.(HO2C–C6H4–CO2H)x(DMF)y(H2O)z (or MIL-68), a new vanadocarboxylate with a large pore hybrid topology : reticular synthesis with infinite inorganic building blocks?
K. Barthelet, J. Marrot, G. Férey, D. Riou
DOI: 10.1039/B312589K
You might also like
How should waste containing 2-Ethyl-4-Methyl-1H-Imidazole-5-Carbaldehyde (CAS: 88634-80-4) be handled?
Waste containing 2-Ethyl-4-Methyl-1H-Imidazole-5-Carbaldehyde (CAS: 88634-80-4) ...
What industries use Triethoxy(octyl)silane (CAS: 1385031-14-0)?
Triethoxy(octyl)silane (CAS: 1385031-14-0) is widely used in the pharmaceuticals...
Are there alternatives to 3-iodo-7-nitro-1H-indazole (CAS: 864724-64-1) in synthesis?
Several alternatives to 3-iodo-7-nitro-1H-indazole (CAS: 864724-64-1) exist in t...
Are there alternatives to Benzene, bis[(trimethoxysilyl)ethyl] (CAS: 266317-71-9) in synthesis?
Yes, there are alternatives to Benzene, bis[(trimethoxysilyl)ethyl] (CAS: 266317...
Is Isothiazole-3-carbonitrile (CAS: 1452-17-1) safe?
Isothiazole-3-carbonitrile (CAS: 1452-17-1) is generally considered safe when us...
Is (3-Chlorophenyl)methanol (CAS: 873-63-2) safe?
(3-Chlorophenyl)methanol (CAS: 873-63-2) is considered low to moderately toxic. ...
How is (2S,3S)-2-Hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-(2-naphthyl)propanoic acid (CAS: 959583-98-3) typically synthesized?
(2S,3S)-2-Hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-(2-naphthyl)pr...
What precautions should be taken when handling Methyl 2-(bromomethyl)-5-methoxybenzoate (CAS: 788081-99-2)?
Proper handling of methyl 2-(bromomethyl)-5-methoxybenzoate requires the use of ...
What is 6,8-Dibromoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 904805-36-3)?
6,8-Dibromoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 904805-36-3) is an aro...
Is 3-Amino-5-bromo-2-pyridinecarbonitrile (CAS: 573675-27-1) safe?
3-Amino-5-bromo-2-pyridinecarbonitrile is considered safe when handled under pro...
Source Journal
Chemical Communications

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry


![4-chloro-N-[5-methyl-2-(7H-pyrrolo[2,3-d]pyrimidine-4-carbonyl)-3-pyridyl]-3-(trifluoromethyl)benzenesulfonamide structure 4-chloro-N-[5-methyl-2-(7H-pyrrolo[2,3-d]pyrimidine-4-carbonyl)-3-pyridyl]-3-(trifluoromethyl)benzenesulfonamide structure](https://static.chemtradehub.com/structs/110/1100318-47-5-127d.webp)

