Regulation of α-chymotrypsin activity on the surface of substrate-functionalized gold nanoparticles

Literature Information

Publication Date 2006-06-02
DOI 10.1039/B605508G
Impact Factor 6.222
Authors

Chang-Cheng You, Rochelle R. Arvizo, Vincent M. Rotello


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Abstract

A gold nanoparticle functionalized with substrates for α-chymotrypsin was fabricated to afford an enzyme modulator that exhibited enzyme-specific activation coupled with general inhibition of other proteases.

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