Isoindoles and dihydroisoquinolines by gold-catalyzed intramolecular hydroamination of alkynes

Literature Information

Publication Date 2006-01-12
DOI 10.1039/B516017K
Impact Factor 6.222
Authors

Daniel Kadzimirsz, Dirk Hildebrandt, Klaus Merz, Gerald Dyker


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Abstract

The title compounds are enantioselectively synthesized in just two prepararative steps, making use of the Ugi-four-component reaction with an amino acid as chiral component, followed by a gold-catalyzed hydroamination.

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