An introduction to thiol redox proteins in the endoplasmic reticulum and a review of current electrochemical methods of detection of thiols

Literature Information

Publication Date 2006-03-09
DOI 10.1039/B515874E
Impact Factor 4.616
Authors

Jaanus Kruusma, Adam M. Benham, J. A. Gareth Williams, Ritu Kataky


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Abstract

This aim of this paper is to expound the complexity of thiol redox systems in the endoplasmic reticulum of eukaryotic cells to the electroanalytical community. A summary of the state of the art in electrochemical methods for detection of thiols gives an insight into the challenges that need to be addressed to bridge the disparity between current analytical techniques and applications in a ‘real’ biological scenario.

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