Planar nitric oxide (NO)-selective ultramicroelectrode sensor for measuring localized NO surface concentrations at xerogel microarrays

Literature Information

Publication Date 2005-11-30
DOI 10.1039/B507981K
Impact Factor 4.616
Authors

Bong Kyun Oh, Mary E. Robbins, Mark H. Schoenfisch


View Original

Abstract

A planar ultramicroelectrode nitric oxide (NO) sensor was fabricated to measure the local NO surface concentrations from NO-releasing microarrays of varying geometries. The sensor consisted of platinized Pt (25 µm) working electrode and a silver paint reference electrode coated with a thin silicone rubber gas permeable membrane. An internal hydrogel layer separated the Pt working electrode and gas permeable membrane. The total diameter of the sensor was ≤50 µm, and demonstrated negligible analyte trapping effects. The sensitivity and response time of the ultramicroelectrode sensor to NO were 0.19 ± 0.07 pA nM−1 and 1–4 s, respectively, with a 5 nM limit of detection. The sensor was employed to correlate the steady-state NO surface concentration and observed platelet adhesion resistance. Results indicate that the required steady-state NO concentration necessary to inhibit platelet adhesion to the micropatterned xerogels depends on the xerogel geometry.

Related Literature

Stability of reverse micelles in rare-earth separation: a chemical model based on a molecular approach

Yushu Chen, Magali Duvail, Philippe Guilbaud, Jean-François Dufrêche

2017-02-10 Paper

DOI: 10.1039/C6CP07843E

Capturing the multiscale dynamics of membrane protein complexes with all-atom, mixed-resolution, and coarse-grained models

Chenyi Liao, Xiaochuan Zhao, Jiyuan Liu, Severin T. Schneebeli, John C. Shelley, Jianing Li

2017-03-06 Paper

DOI: 10.1039/C7CP00200A

Tuning calcium biosensors with a single-site mutation: structural dynamics insights from femtosecond Raman spectroscopy

Sean R. Tachibana, Longteng Tang, Yanli Wang, Weimin Liu

2017-02-13 Paper

DOI: 10.1039/C6CP08821J

Effects of Ge and Sn substitution on the metal–semiconductor transition and thermoelectric properties of Cu12Sb4S13 tetrahedrite

Yasufumi Kosaka, Koichiro Suekuni, Katsuaki Hashikuni, Yohan Bouyrie, Michihiro Ohta

2017-03-06 Paper

DOI: 10.1039/C7CP00351J

Co2SnO4 nanoparticles as a high performance catalyst for oxidative degradation of rhodamine B dye and pentachlorophenol by activation of peroxymonosulfate

Alexandre Barras, Ahmed Addad, Brigitte Sieber, Mokhtar Férid, Sabine Szunerits, Rabah Boukherroub

2017-02-02 Paper

DOI: 10.1039/C6CP08576H

In search of the best DFT functional for dealing with organic anionic species

José L. Borioni, Marcelo Puiatti, D. Mariano A. Vera, Adriana B. Pierini

2017-03-03 Paper

DOI: 10.1039/C6CP06163J

You might also like

Compound Q&A

What are the main uses of 1H-Indazole-6-carbonitrile (CAS: 141290-59-7)?

1H-Indazole-6-carbonitrile finds applications in pharmaceuticals, where it serve...

141290-59-71H-Indazole-6-carbon...
Compound Q&A

How should waste containing Dioctyl (2E)-2-butenedioate (CAS: 2997-85-5) be handled?

Waste containing Dioctyl (2E)-2-butenedioate (CAS: 2997-85-5) should be collecte...

2997-85-5Dioctyl (2E)-2-buten...
Compound Q&A

What industries use Sodium [(1,2-benzoxazol-3-ylmethyl)sulfonyl]azanide (CAS: 68291-98-5)?

Sodium [(1,2-benzoxazol-3-ylmethyl)sulfonyl]azanide is primarily used in pharmac...

68291-98-5Sodium [(1,2-benzoxa...
Compound Q&A

Are there alternatives to Dimethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-pyridinedicarboxylate (CAS: 741709-66-0) in synthesis?

Dimethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-pyridinedicarboxyla...

741709-66-0Dimethyl 4-(4,4,5,5-...
Compound Q&A

How should waste containing 2-Fluoro-6-hydrazinopyridine (CAS: 80714-39-2) be handled?

Waste containing 2-Fluoro-6-hydrazinopyridine (CAS: 80714-39-2) should be manage...

80714-39-22-Fluoro-6-hydrazino...
Compound Q&A

What is 6-Formyl-2-pyridinecarboxylic acid (CAS: 499214-11-8)?

6-Formyl-2-pyridinecarboxylic acid is an organic compound with the molecular for...

499214-11-86-Formyl-2-pyridinec...
900874-91-13-(3,4-dimethoxyphen...
Compound Q&A

How is 9H-Tribenzo[b,d,f]azepine (CAS: 29875-73-8) typically synthesized?

9H-Tribenzo[b,d,f]azepine is typically synthesized via a multi-step process invo...

29875-73-89H-Tribenzo[b,d,f]az...
Compound Q&A

How is 1-Cyclopropyl-7-ethoxy-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 1797982-51-4) typically synthesized?

1-Cyclopropyl-7-ethoxy-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxyli...

1797982-51-41-Cyclopropyl-7-etho...
Compound Q&A

How should waste containing Methyl 3-oxo-1,2,3,4-tetrahydro-6-quinoxalinecarboxylate (CAS: 671820-52-3) be handled?

Waste containing Methyl 3-oxo-1,2,3,4-tetrahydro-6-quinoxalinecarboxylate (CAS: ...

671820-52-3Methyl 3-oxo-1,2,3,4...

Source Journal

Analyst

Analyst
CiteScore: 7.8
Self-citation Rate: 5.6%
Articles per Year: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.