Aptamer biosensor for label-free impedance spectroscopy detection of proteins based on recognition-induced switching of the surface charge

Literature Information

Publication Date 2005-07-12
DOI 10.1039/B506571B
Impact Factor 6.222
Authors

Marcela C. Rodriguez, Abdel-Nasser Kawde, Joseph Wang


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Abstract

The recognition of proteins by aptamer-modified electrode transducers reverses the surface charge and leads to a novel label-free impedance spectroscopy bioelectronic detection protocol based on a decrease in the electron transfer resistance.

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