Lewis acid-catalyzed stereospecific ring expansion of aziridine-2-carboxylates to imidazolidin-2-ones

Literature Information

Publication Date 2005-05-09
DOI 10.1039/B503750F
Impact Factor 6.222
Authors

Min Sung Kim, Yong-Woo Kim, Heung Sik Hahm, Jae Won Jang, Won Koo Lee, Hyun-Joon Ha


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Abstract

Lewis acid-catalyzed ring expansion reaction of chiral aziridine-2-carboxylate proceeds regio- and stereospecifically to yield enantiomerically pure 4-functionalized imidazolidin-2-ones in high yields.

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