Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy

Literature Information

Publication Date 2005-01-05
DOI 10.1039/B415578E
Impact Factor 6.222
Authors

Shuwei Li, Nishanth Marthandan, Dawn Bowerman, Harold R. Garner, Thomas Kodadek


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Abstract

We report here a strategy for the photolithographic synthesis of diverse, spatially addressable arrays of cyclic peptides which employs a differential deprotection strategy for the combinatorial addition of side chains to a pre-fabricated cyclic core.

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Chemical Communications
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