Lewis acid-catalyzed hydrogenation: B(C6F5)3-mediated reduction of imines and nitriles with H2‡
Literature Information
Preston A. Chase, Titel Jurca, Douglas W. Stephan
The Lewis acidB(C6F5)3 has been found to be an efficient catalyst for the direct hydrogenation of imines and the reductive ring-opening of aziridines with H2 under mild conditions; addition of a bulky phosphine allows for the reduction of protected nitriles.
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![Imidazo[1,2-c]pyrimidine structure Imidazo[1,2-c]pyrimidine structure](https://static.chemtradehub.com/structs/274/274-78-2-8b4c.webp)



