A pyrimidine-like nickel(ii) DNA base pair

Literature Information

Publication Date 2005-01-19
DOI 10.1039/B415426F
Impact Factor 6.222
Authors

Christopher Switzer, Dongwon Shin


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Abstract

4-(2′-Pyridyl)-pyrimidinone deoxyriboside is synthesized and characterized as a DNA metallo base-pair; this novel nucleoside forms a self-pair in the presence of Ni(II) and stabilizes double helical DNA to the same extent as a G·C pair.

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