Stereospecific peptide folds. A rationally designed molecular bracelet

Literature Information

Publication Date 2004-09-20
DOI 10.1039/B410532J
Impact Factor 6.222
Authors

Soumendra Rana, Bijoy Kundu, Susheel Durani


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Abstract

A canonical planar β-hairpin peptide, stereochemically reengineered into a semicircular bracelet type motif by L-to-D stereochemical inversion in two pairs of its cross-strand neighbor residues, displays protein like ordering including two-state behavior in H2O, which is unusual for a small peptide of this size.

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