Very high pressure HPLC with 1 mm id columns

Literature Information

Publication Date 2004-04-28
DOI 10.1039/B405242K
Impact Factor 4.616
Authors

Luis A. Colón, José M. Cintrón, Jason A. Anspach, Adam M. Fermier, Kelly A. Swinney


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Abstract

Theoretical calculations and experimental data indicate that very high pressure HPLC can be performed using 1 and 1.5 mm id columns, and contrary to previous beliefs, the frictional heating generated does not appear to be detrimental to the separation.

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