Enantiopure oxazolidinones as chiral acids in the asymmetric protonation of N-Boc pyrrole derived enolates

Literature Information

Publication Date 2004-02-16
DOI 10.1039/B316719D
Impact Factor 6.222
Authors

David R. Carbery, Timothy J. Donohoe


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Abstract

The first use of geminally disubstituted oxazolidinones as chiral protonating agents is described: these new acids are able to directly protonate an enolate generated by the ammonia free partial reduction of an electron deficient pyrrole and give up to 68% ee in the pyrroline product.

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