Novel and efficient synthesis of difficult sequence-containing peptides through O–N intramolecular acyl migration reaction of O-acyl isopeptides
Literature Information
Youhei Sohma, Masato Sasaki, Yoshio Hayashi, Tooru Kimura, Yoshiaki Kiso
A novel and efficient method for the synthesis of difficult sequence-containing peptides has been developed based on the synthesis of O-acyl isopeptides followed by an O–N intramolecular acyl migration reaction, resulting in a remarkable improvement of the yields.
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