Alkaline salt-catalyzed aza Diels–Alder reactions of Danishefsky’s diene with imines in water under neutral conditions

Literature Information

Publication Date 2003-02-11
DOI 10.1039/B300880K
Impact Factor 6.222
Authors

Catherine Loncaric, Kei Manabe, Shū Kobayashi


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Abstract

Two- or three-component aza Diels–Alder reactions of Danishefsky’s diene with imines or aldehydes and amines in water took place smoothly under neutral conditions in the presence of a catalytic amount of an alkaline salt such as sodium triflate to afford dihydro-4-pyridones in high yields.

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