Asymmetric protonation of lithium enolates of α-amino acid derivatives with α-amino acid-based chiral Brønsted acids
Literature Information
Kentaro Futatsugi, Akira Yanagisawa, Hisashi Yamamoto
The reaction of lithium enolates of α-amino acid derivatives with chiral amides, easily synthesized from L-tert-leucine, gives corresponding optically active unnatural α-amino acid derivatives with up to 87% ee.
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